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The increase in lactate that we detected points towards a defect in oxidative energy metabolism, but this conclusion must be treated cautiously given the difficulty of measuring lactate in the presence of the much larger and broader macromolecule (MM) resonance at ~1.35 ppm, with the lactate signal being a small shoulder on that peak (Fig

We found evidence that despite their significant within-group correlation, when compared with healthy controls, glutamate and GSH levels were less tightly correlated among patients with FEP

It's our job to cut through the noise and look at what the science actually says

Am J Psychiatry 2000

Li et al., 2024b)