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Consumers may encounter: Standard oral reduced glutathione Liposomal glutathione S-acetyl glutathione Sublingual or buccal glutathione Intravenous glutathione N-acetylcysteine, or NAC Glycine and GlyNAC Protein and other nutritional precursors These are not simply different brand names for the same intervention

Approaches such as intrathecal, intracerebroventricular, and intraparenchymal injections, as well as transient BBB disruption, have been employed to deliver drugs with limited CNS bioavailability (Rezaee et al., 2025)

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Taken together, the above-mentioned data suggest that GSH might serve as an important wound signal that triggers wound-induced systemic [Ca 2+ ] cyt transmission, activates JA biosynthesis, and regulates plant defense responses