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hCMEC/D3 cultures conserve immune profiles and permit the transmigration of immune cells (Daniels et al., 2013)

Consistently, increased oxidative stress, and accumulation of malondialdehyde and 4-hydroxynonenal are observed in the hepatocytes of diabetic rats [114]

& Waters, M

The combined effect of dyslipidemia and STZ-induced -cell damage leads to stable hyperglycemia, therefore this model mirrors human T2DM, where abnormal lipid metabolism is a key driver of complications

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