M1 macrophages secrete pro-inflammatory cytokines such as IL-1, IL-6, and TNF-, which trigger further inflammatory responses in the synovium and contribute to cartilage destruction and osteophyte formation, thus exacerbating OA progression (Marchev et al., 2017
12 mg/kg at 5 days
(2016) 146:410S5S
Supporting Your Treatment Plan In addition to medications: Eat anti-inflammatory foods: vegetables, berries, lean proteins, healthy fats Exercise for strength and mobility Sleep deeply and consistently Consider supplements: omega-3s, curcumin, vitamin D, magnesium Explore supportive treatments: peptides (BPC-157, thymosin alpha-1), regenerative medicine (platelet-rich plasma, bone marrow stem cells) for joint repair if inflammation is controlled Final Thoughts RA may have a genetic component, but your future is not set in stone
At this stage most users will not really see any change, some may notice a very subtle glow or slightly better clarity of the skin, if theres anything at all