It is also conceivable that GSH depletion in the ER results in intraluminal redox imbalance, leading to phosphorylation of eIF2 and activation of ATF6 and CHOP [82], [83]
And multi-level anti-inflammatory modulation reduces damaging cytokines like IL-6 and TNF-alpha
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Cells resuspended in the growth medium (GM, DMEM containing 10% fetal bovine serum (FBS, Life Technologies) and 1% anti-anti), and the single cells were seeded in a cell culture flask
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