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The oxidative damages of biomolecules specifically of DNA due to the accumulation of hydroperoxides and other ROS ultimately lead to the loss of cell viability or cell death through various death mechanisms like apoptosis, autophagy, necrosis, ferroptosis, and mitotic catastrophe (Fig

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Prolonged air exposure should be avoided because the methionine at position 27 is oxidation-sensitive

ZnO and TiO nanoparticles induce oxidative stress and membrane damage, while copper nanoparticles release Cu ions that impair amino acid synthesis and damage nucleic acids [77, 78]

The hypothesis extended to the possibility that if BPC-157 were introduced before the occurrence of TBI, it might show an improved ratio of conscious/unconscious/death states in the test subjects