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The warnings will reduce smoking and the appeal of cigarettes, and thus prevent cancer and other diseases. The society says tobacco use is the leading preventable cause of disease and death in this country, with 46,000 Canadians killed each year

Given the vast array of data available on epithelial cells, the data reviewed here will focus on immune modulation of and toxicity to epithelial cells from mucosal surfaces that have the heaviest exposure to e-cigarette aerosols: oropharynx and lower respiratory tract (Table 9)

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