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The use of novel carriers such as liposomes, nanoparticles, sphingosomes, emulsomes, ethosomes, transferosomes, proniosomes and phytosomes has successfully improved targeted delivery and therapeutic efficacy of poorly aqueous soluble plant drugs [84, 85]
The FDA has not approved BPC-157 for any human use
Labeled "for research use only, not for human consumption." No FDA oversight on manufacturing
It is worth noting that the anticancer and immunomodulatory role of bilirubin in nanomedicines was overlooked in some of the above experiments, which focused on its high photothermal conversion efficiency as a photosensitizer on tumors, without noting that the anticancer role of bilirubin/biliverdin as a ROS scavenger in its own right should not be underestimated
