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Cortisol increases the expression of genes for metallothionein and ZIP-14, which accumulate zinc in the liver and adipose tissue, promoting hypozincemia in obese people (157)

Stable Gastric Pentadecapeptide BPC 157 as a Therapy and Safety Key: A Special Beneficial Pleiotropic Effect Controlling and Modulating Angiogenesis and the NO-System, Sikiric P, Seiwerth S, Skrtic A, Staresinic M, Strbe S, Vuksic A, Sikiric S, Bekic D, Soldo D, Grizelj B, Novosel L, Beketic Oreskovic L, Oreskovic I, Stupnisek M, Boban Blagaic A, Dobric I, Pharmaceuticals (Basel), Pharmaceuticals, 2025 Jun 19;18(6):928

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Research focuses on molecular mechanisms in in vitro models and preclinical systems

Severe nausea requiring medication discontinuation affects approximately 2-4% of users