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Using it topically leads to whiter, clearer skin due to this mechanism

In addition, treatment with phenformin, another biguanide, mirrored the effects of metformin, significantly increasing GLUT1 and HK2 mRNA expression in both cell lines (Supplementary Fig

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We dont yet know if its due to their unhealthy saturated fats, pollutants or some combination of these factors. This doesnt necessarily mean burgers are off the table