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The collect term reactive oxygen species (ROS) describes the chemical species that are formed upon incomplete oxygen reduction, which are significant mediators of inflammation [4]

Moreover, UMOD overexpression correlates with diminished UA excretion, renal fibrosis, immune cell infiltration, and progressive renal failure

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Copper deposits in lysosomes, visualized with rodanine staining, are observed, but their distribution is not uniform in the liver parenchyma, and they are not present in every WD patient [14]