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10.1101/cshperspect.a033688 110 MartinK

These effects appear to be associated with the subsequent spreading lesions in the entire digestive tract, increased liver lesions severity, and the events involved in the anastomosis

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Pharmacological interaction of drugs with antigen-specific immune receptors: the p-i concept

Although many pathological stimuli can trigger necroptosis, the most typical pathway for inducing necroptosis is TNF and FAS signaling, in which CASP8 inhibition activates necrosomes (a multi-protein complex containing RIPK1, RIPK3, and MLKL) to trigger necroptosis [113]