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Dosimetry, a major issue Different ways to express doses and different dose ranges used When considering the studies dealing with the toxicity of e-cigarettes assessment, in addition to the heterogeneity of e-cigarette products, biological models, or exposure conditions observed, there is also a huge disparity in the doses used as well as in the way they are expressed as shown in Table 2

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Among individuals who use tobacco for chewing, it was observed that 66% had a sperm count below the standard criteria set by the World Health Organization (WHO), 85.5% had impaired sperm motility, and 28.4% had abnormal sperm morphology