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The shift from combustible to HTP use is in line with the Japanese NHNS data and suggests that the introduction of HTPs in Japan has not increased overall tobacco product use but appears to have increasingly replaced combustible tobacco products

This may require a phone call to your MSA representative to explain the situation

A half pack contains 10 cigarettes

Among the 36 smokingoutcome pairs analyzed, smoking fracture was the only binary riskoutcome pair, which was due to limited data on the doseresponse risk of smoking on fracture 202

Enhanced penetration of nitrosonornicotine across oral mucosa in the presence of ethanol