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The ATP-P2X7-NLRP3 pathway seems to be a predominate mediator of stress-induced inflammation, holding great relevance for a wide range of neuropsychiatric (and systemic) illnesses [1]

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GV-1001 is currently undergoing phase II clinical trials for liver cancer and NSCLC (non-small-cell lung cancer) as well as a phase III trial for pancreatic cancer [86]