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This age-related NAD+ depletion impairs mitochondrial energy production, reduces SIRT1 activity, compromises DNA repair mechanisms, and accelerates cellular senescence

Osteogenic growth peptide C-terminal pentapeptide [OGP(10-14)] acts on rat bone marrow mesenchymal stem cells to promote differentiation to osteoblasts and to inhibit differentiation to adipocytes

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[DOI] [PubMed] [Google Scholar] 83.Konosic S., Petricevic M., Ivancan V., Konosic L., Goluza E., Krtalic B., Drmic D., Stupnisek M., Seiwerth S., Sikiric P