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Bacterial infections are treated with antibiotics, which work faster

Nrf2 activation regulates antioxidant responses to modify cellular redox states from predominantly pro-oxidant to antioxidant, and, in an antioxidant environment, macrophage phenotypes shift from M1 pro-inflammatory to M2 anti-inflammatory, reducing the probability of cytokine storms, ARDS, and lethality (Tan et al., 2016

Some effects improve after stopping

Among all the combinations, the AZD-5991 and CB-839 combination showed solid synergism in antiproliferative activity and apoptosis induction