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Therefore, true baseline data at the time of initiating biologic treatment may not have been captured, and psoriasis BSA involvement and PRO measures may have improved before enrollment in the registry

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Elevated expression of asparagine synthetase (ASNS), which transfers an amide group from glutamine to aspartate for asparagine formation, is associated with resistance to asparaginase therapy in ALL (Lomelino et al., 2017)