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Keywords: disulphide-bond formation, endoplasmic reticulum, glutathione, oxidative stress, reactive oxygen species Introduction Glutathione (GSH) is a tripeptide (L--glutamyl-L-cysteinyl-glycine) that is synthesized in the cytosol from the precursor amino acids glutamate, cysteine and glycine

Lipid peroxidation and iron Being a transition metal, iron can effortlessly exchange electrons and switch between ferrous (Fe +2 ) and ferric (Fe +3 ) forms [148]