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When Symptoms Worsen: Understanding the Adjustment Period The period following B12 injection therapy can be challenging for some patients, with symptoms sometimes temporarily intensifying before improvement becomes apparent

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Additionally, in phase 2 studies in people with MASH and liver fibrosis, survodutide not only significantly improved liver steatosis, but also led to histologic improvement of MASH without worsening fibrosis in 4362% of participants, versus 14% with placebo [41]

Once mixed, the solution can be stored in the refrigerator for a short time, but its best to use it as soon as possible to ensure maximum potency

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