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Due to its role in combating oxidative stress, glutathione may help reduce signs of aging, contributing to improved skin appearance and overall vitality

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Hepatic stellate cells (HSCs) are central drivers of liver fibrosis and cancer progression, differentiating into myofibroblasts and cancer-associated fibroblasts

Studies have found that berberine attenuates ischemia-reperfusion injury through NF-B nuclear translocation in mice with transient cerebral artery occlusion, however, this neuroprotective effect was more pronounced at the high dose (50 mg/kg) than the low dose (25 mg/kg) (Zhu et al., 2018)

The physiological adaptations over time need to be considered