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Several GDF-15 agonists are undergoing early phase clinical trials including NNC0247-0829 and JNJ-9090/CIN-109

GHK-Cu primarily supports tissue repair, collagen production, and visible skin rejuvenation, whereas Epithalon works deeperpromoting cellular longevity, telomere support, and optimized biological aging

In summary, exosomes from HACE patients potentially impact cognitive dysfunction by inducing oxidative stress, promoting neuroinflammation, and disrupting neurodevelopment

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