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Nicotine is a specific biomarker of exposure to tobacco smoke, either active or ETS, but due to its short half life (1-3 hours) it has limited value as a marker of exposure

Among the findings: More than 50% of adults aged 40 to 59 who smoked developed cardiovascular disease and were almost twice as likely to die of a fatal heart attack, stroke, or heart failure without previous warning

Additionally, a study in Pediatrics notes that these ultrafine particles may make their way into the circulatory system, potentially causing inflammation and cardiovascular disease

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Standard King-Size Cigarette Box A regular or normal cigarette packaging with cigarette box measurements of 3.35 x 2.17 x 0.79 inches (85 x 55 x 20 millimeters)