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Clinically, reduced glutathione is administered via intravenous injection as a direct and rapid antidote to paracetamol poisoning

[2] Keller JL, et al

That said, the most clear and compelling cases for vitamin IV therapy are instances where a persons GI tract is impaired, interfering with macronutrient absorption (5)

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If this is the case, treatment can be done with lifelong vitamin B12 injections, but it should be noted that small amounts of vitamin B12 can be absorbed without intrinsic factor protein