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10.1093/jnen/62.7.723 16 BodiniB.VeroneseM.Garca-LorenzoD.BattagliniM.PoirionE.ChardainA.et al

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An aspect that is acquiring relevance in muscle physiology is the endocrine nature of this organ by releasing an array of muscle-derived signaling molecules (myokines) that include irisin and myostatin, cytokines and receptor antagonists known to communicate with other organs and to regulate myocytes proliferation and differentiation [107,108]