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Some cancer cells are very dependent on Mcl-1, which is the last line of defense keeping the cell from dying

[ 309 ] Another study suggests a thermosensitive gelnano system for EC treatment through small interfering RNA targeting BACH1 and p53 activator PRIMA1, restoring antitumor immune responses, has potential for clinical application

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By emphasizing these research priorities, we aim to stimulate scientific progress that could lead to innovative intervention strategies for ferroptosis-related disorders, particularly in malignancies where macrophage function and iron metabolism present promising therapeutic targets

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