A single-blind, randomized, controlled trial (NCT01964001) in patients with primary HCC found that CoQ10 supplementation for 12 weeks post-surgery significantly improved antioxidant capacity and reduced oxidative stress and inflammation levels
By modulating autophagy and Nrf2 signaling pathways, melatonin slows the progression of colitis-associated colon cancer in mice
Nonetheless, its short and long-term cardiotoxic effects are of foremost clinical significance (Podyacheva and Toropova, 2022)
L-Carnitine intake and high trimethylamine N-oxide plasma levels correlate with low aortic lesions in ApoE-/-transgenic mice expressing CETP
Gandhi KA, Goda JS, Gandhi VV et al (2019) Oral administration of 3,3-diselenodipropionic acid prevents thoracic radiation induced pneumonitis in mice by suppressing NF-kB/IL-17/G-CSF/neutrophil axis