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The OINDP classification is important because it signals that standard pharmaceutical testing protocols are insufficient nasal sprays require a specialized suite of device performance tests (spray pattern, plume geometry, droplet size distribution, dose uniformity) that are specific to this dosage form and that are detailed in dedicated FDA guidance documents

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These initial clinical results support the concept of DPP1 inhibition as a potential therapeutic strategy across multiple inflammatory diseases that involve excessive NSP secretion or neutrophil dysregulation and hyperresponsiveness