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The study did not break down results by specific medication, so we cannot determine whether tirzepatide users experienced more or less improvement than semaglutide users

This is supported by the observation that TYMS can function like a tumor promoter (oncogene), while a reduction in TYMS activity is linked to a lower risk of cancer (113, 114)

This prevents tumor endothelial cells from properly responding to physiological stimuli (25)

Animal studies using euglycemic clamp techniques, the gold standard for insulin sensitivity assessment, confirmed that chronic AOD-9604 treatment produced no adverse effects on insulin sensitivity