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Instead, research points to activity across multiple interconnected systems, including modulation of the nitric oxide (NO) system, upregulation of growth factor expression (notably VEGF, EGF, and FGF pathways), promotion of angiogenesis, and activation of the FAK-paxillin signalling pathway involved in cell migration and tissue organisation

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Timing Optional Monitoring guidance is GHRH/GH-axis pathway-based, with IGF-1 used as the main downstream monitoring marker

doi: 10.1016/j.csbj.2019.12.013 99 PotockM.PejcharP.GutkowskaM.Jimnez-QuesadaM

Enteric-coated aspirin induces small intestinal injury via the nrf2/gpx4 pathway: A promising model for chronic enteropathy