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In contrast, somewhat lower removal of isoprene (82%), acetaldehyde (60%) and acetone (85%) was observed, although the amounts removed were very high (250650 g/cigarette)

These symptoms vary in severity and include irritability, anxiety, depressed mood, difficulty concentrating, increased appetite, and sleep disturbances

[ citation needed ] Since the beginning of the 21st century, low-tar and menthol variants are also sold

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