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Apr 2017;18:23-30

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This protective effect occurs through the preservation of S-adenosylhomocysteine hydrolase activity, which helps inhibit ferroptosis ( 2.2 Mitochondrial dysfunction in neurodegenerative pathology Mitochondria are central regulators of cellular respiration, metabolism, energy production, intracellular signaling, and free radical generation ( 2.3 Relationship between oxidative stress and neurodegenerative disorders With aging, redox imbalance develops alongside elevated levels of ROS and reactive nitrogen species (RNS)