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Sexual addiction is not officially recognized as a clinical diagnosis in the DSM-5 but is classified as an impulse-control disorder in the ICD-11

While cardiac puncture offers better sample purity and volume, IV methods are less invasive and allow for repeated measurements, though they require careful handling to minimize animal stress and ensure welfare 17

Although no OA biomarker class is ready for routine clinical use, biomarker-based stratification may still help early detection and precision trial design