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The decarboxylation and dehydration of the cysteine part of the protonated molecules was observed yielding fragments with m/z 209 for APAP-CYS and 167 for PAP-CYS (Fig

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In addition to the existence of Lewy bodies (intracellular cytoplasmic proteins), mitochondrial dysfunction and oxidative stress play vital roles in PD progression [5, 6]