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Paraxanthine, the primary metabolite of caffeine, has also been shown to improve cognitive function to a greater extent than caffeine in animal models [10] and humans [36]

Note that immunoreactivity was lost after chemical fixation possibly attributed to derivatization of conserved lysine residues in the epitope ( Supplementary Fig

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Bacteriostatic water is the preferred diluent because its 0.9% benzyl alcohol content inhibits microbial growth, extending the usable shelf life of the reconstituted solution to 2830 days under refrigerated conditions