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Portable air purifiers also may not be particularly useful for: mold nicotine and other gaseous pollutants animal dander, especially from involuntary rodent infestations cockroach allergens some types of VOCs larger, heavier allergens, such as dust mites and pollen, which may settle to the ground more quickly than air purifiers can capture them Despite their potential benefits, air purifiers may be futile if you dont take other steps to create cleaner air in your home, too