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According to the applicant, the DETOUR System received Breakthrough Device designation from FDA on September 2, 2020 for percutaneous revascularization of symptomatic femoropopliteal lesions 200mm to 460mm with a chronic total occlusion 100mm to 425mm, and/or moderate-to-severe calcification, and/or in-stent-restenosis in patients with severe peripheral arterial disease

The first is that the Km of ChaC1 towards glutathione is in the range of 2 mM due to levels of glutathione in the cytoplasm ranging between 1-10 mM

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Peptides should not replace diagnosis, rehabilitation, progressive loading, mobility work, strength training, or appropriate medical care

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