It is what good clinical judgment has always required: patient selection, transparent informed consent about the state of the evidence, quality sourcing standards, systematic outcome tracking, and a willingness to update your position as the data matures
Addition of a gastrointestinal microbiome modulator to metformin improves metformin tolerance and fasting glucose levels
They also help to reduce the duration and severity of illnesses, making them essential nutrients for maintaining optimal wellbeing and vitality
Della Nera G, Sabatino L, Gaggini M, Gorini F, Vassalle C (2023) Vitamin D determinants, status, and antioxidant/anti-inflammatory-related effects in cardiovascular risk and disease: not the last word in the controversy
Chemically, yes, because both are highly purified water