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The mediation proportions were 26.1% for blood glucose, 11.8% for insulin level, 6.6% for C-reactive protein, 0.6% for cholesterol (not significant), and 0.8% for systolic blood pressure (not significant)

Oral bioavailability is limited due to enzymatic breakdown in the gastrointestinal tract, yet some studies show systemic benefit at doses of 5001500 mg daily

PMID: 1299794 Kovalzon VM (2006) Delta sleep-inducing peptide (DSIP): a still unresolved riddle

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