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They are, however, a good principled starting point for anyone in the business of developing principled excise taxes

A 1-month exposure study investigated the impact of IQOS on rat ultrastructural lung airways and found that IQOS exposure led to a severe remodeling of smaller and larger airways, increased tissue ROS, and promoted oxidative DNA damage

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One study found that the treatment significantly increased stop smoking rates from weeks 15 to 24 of treatment, with 32.1% of people breaking the habit after using varenicline, compared to just 6.9% on a placebo

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