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In Experiment 2, oocyte viability, early apoptosis, mortality, oxidative status, mitochondrial membrane potential and distribution, DNA fragmentation, maturation rates, meiotic spindle and chromosome organization, fertilization rates, embryo production and cumulus cell parameters were also analyzed by factorial ANOVA followed by the Bonferroni post hoc correction
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In this process, glutathione forms a reversible mixed disulfide bond with the vulnerable cysteine residues of cellular proteins, effectively shielding them from permanent oxidative destruction