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Recent elegant work has definitively identified that TP53 missense mutations in myeloid malignancies result in a dominant-negative effect without evidence of neomorphic gain-of-function activities, ultimately leading to a selection advantage when exposed to DNA damage.12 Thus, restoring wild-type function in TP53 mutant clones would be of profound beneficial impact

Structural and evolutionary studies on sterol 14-demethylase P450 (CYP51), the most conserved P450 monooxygenase: I

If someone was magnesium-deficient before the infusion, they may feel benefits, like reduced muscle tension, calmer nerves, or better sleep, for a full day or more, even though blood levels have already returned to normal

Anorectic role of high dietary leucine in farmed Atlantic salmon ( Salmo Salar L.): effects on feed intake, growth, amino acid transporters and appetite-control neuropeptides

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