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The neuroscience: how the brain responds to ritual replacement When you inhale through a vapourless device, several things happen in the brain: Dopamine modulation: Flavour and sensory stimulation trigger mild dopamine release, reducing cravings

130 Indirect effects of tobacco smoke on DCs Disruption of the bronchial epithelial cell homeostasis has been shown to initiate the inflammatory cascade that leads to the development of asthma (reviewed in ref