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Red blood cell formation: B12 helps create healthy red blood cells that carry oxygen throughout your body

This is because up to 25% or more of the energy produced through oxidative-phosphorylation is lost as reactive oxygen species (ROS), or free radicals

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In addition, CRISPR-Cas9 targeting of KEAP1 , an inhibitor of the NRF2 antioxidant pathway, lead to resistance to palbociclib and has been shown to induce resistance to ferroptosis 28,29,30

doi: 10.1038/s41586-024-07142-4 84 LinJ.MiaoJ.SchaeferK