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The fact that tobacco exposure appeared similar between combined smokers and tobacco-only smokers strengthens the argument that cannabis may be contributing something beyond tobacco alone, whether through its own direct carcinogenic effect or through additive pulmonary toxicity

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Additionally, if you have more receptors for certain chemicals (like caffeine), then it may take fewer puffs to feel their effects as well than someone who doesnt have as many receptors for those chemicals

In CKB, two-thirds of men smoked at baseline, with little dependence of smoking prevalence on age