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Featuring just over three minutes of ragtime music, this lively tune could have easily fit on a Scott Joplin record

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In moderate-to-severe HS, apremilast has shown promising activity in several case reports, a small randomized trial and an open-label phase 2 study, with clinically relevant reductions in inflammatory lesions and DLQI, supporting its consideration as an oral option when standard systemic therapies are inadequate or not tolerated [88,89,90,91]