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Layering: Start with salicylic acid first

Previous reports suggested that system Xc - is involved in lysosomal pH regulation [21], but this study for the first time demonstrates direct relevance of this mechanism for iron handling and ferroptosis

10.1016/0024-3205(75)90089-2 Life Sci

Specifically, fluoxetine-induced hepatic lipid accumulation involves prostaglandin endoperoxide synthase 1, leading to increased levels of 15-deoxy- 12,14 PGJ2, thereby exacerbating liver damage through complex biochemical pathways (296)

Introduction More than 50 years ago, the free radical theory of aging suggested that endogenous oxygen radicals generated in cells were a risk factor for aging-related diseases, and a thiol compound such as cysteine was expected to slow the aging process [1]