This might arise from a reporting bias by subjects who relapsed, being less likely to admit symptoms resulting from their inability to quit the habit even if they reported more phlegm
[The FDA] want to shift people to alternative products like vaping, which is good, but there are a number of risks, she said, pointing out that reducing nicotine levels could also have other unintended consequences including people smokers smoking more cigarettes, or even an increase in black market activity
Keith Richards smoking on set of the music video 'Waiting on a Friend', East Village, NYC July 2, 1981
97 The metabolic detoxification that occurs in the liver starts with phase I enzymes that convert a toxic chemical into a less harmful chemical that can be metabolized by phase II enzymes
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