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PubMed, Skaper, Stephen D., et al

COX-2 is an N-glycoprotein with 4 glycosylation sites 33 , and it has been shown that inhibition of COX-2 N-glycosylation by site-directed mutagenesis or pharmacologically using an N-glycosylation inhibitor leads to the production of a COX-2 protein with reduced molecular mass and activity 34

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3.2 Metal-organic frameworks The MOFs, assembled from metal ions and organic ligands via coordination bonds, have attracted growing interest in biomedical applications owing to their biocompatibility, biodegradability, adjustable structures, and diverse functions (Liang and Liang, 2020