In practical use, Virginias by themselves are a wonderful smoke, if a bit hot due to the high sugar content and low oils, which can slow down the burn rate
It binds to nicotinic acetylcholine receptors in the adrenal medulla and autonomic ganglia, stimulating the release of catecholamines such as norepinephrine and epinephrine
Dentist-supervised bleaching, custom trays, or cosmetic solutions like veneers can reach pigmentation that DIY efforts cant touch
Shamanism, it would seem, is a matter of degree rather than kind, and although none but the most insecure or inept would openly admit as much, all those involved in sharing tobacco and ayahuasca are scaling the rungs of shamanic initiation
Eisberg came back with a definitive answer: the best match was The Minneapolis Foundation (TMF)